Spastic paraplegia 4 (SPG4; also known as SPAST-HSP) is characterized by insidiously progressive bilateral decreased-limb gait spasticity. More than 50% of affected folks have some weak spot during the legs and impaired vibration perception within the ankles.????? ??? ????? ???? ????.????? ???? ??? ??? ??? ???? ?????.A chromosomal abnormality consi